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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MED13 All Species: 26.36
Human Site: T977 Identified Species: 48.33
UniProt: Q9UHV7 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UHV7 NP_005112.2 2174 239318 T977 Q E Y G T A Y T P Q T H T S F
Chimpanzee Pan troglodytes XP_001138050 2188 240763 T991 Q E Y G P A Y T P Q T H T S F
Rhesus Macaque Macaca mulatta XP_001110128 2174 239364 T977 Q E Y G P A Y T P Q T H T S F
Dog Lupus familis XP_537704 2182 240593 T986 Q E Y G P A Y T P Q T H T S F
Cat Felis silvestris
Mouse Mus musculus Q5SWW4 2171 238573 T976 Q D Y G P A Y T P Q T H A S F
Rat Rattus norvegicus NP_001100505 2040 223488 P875 I L P S P S T P R F P T P R T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509907 2170 238695 T974 Q E Y G A A Y T P Q T H T P F
Chicken Gallus gallus XP_415884 2225 244861 T1028 Q E Y G P A Y T P Q T H T P F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A2VCZ5 2102 230974 S918 E E C V Y R P S W T V G K L G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KTX8 2618 280005 H1221 L Q Q R I Q L H Q Q K L Q Q L
Honey Bee Apis mellifera XP_393643 1982 216109 Q817 P L T N L P S Q S L P P V T L
Nematode Worm Caenorhab. elegans Q93442 2862 325119 Y1140 L K S K K K K Y D T P V T S K
Sea Urchin Strong. purpuratus XP_001203054 1127 123639
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.8 97.7 94.1 N.A. 92.5 87.8 N.A. 89.5 84.6 N.A. 64.8 N.A. 24.7 35 21 25.7
Protein Similarity: 100 98.3 98.4 96 N.A. 96.4 91.2 N.A. 94 90.5 N.A. 76.9 N.A. 41.3 51.5 37.4 36
P-Site Identity: 100 93.3 93.3 93.3 N.A. 80 0 N.A. 86.6 86.6 N.A. 6.6 N.A. 6.6 0 13.3 0
P-Site Similarity: 100 93.3 93.3 93.3 N.A. 86.6 6.6 N.A. 86.6 86.6 N.A. 20 N.A. 13.3 6.6 20 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 54 0 0 0 0 0 0 8 0 0 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 0 0 8 0 0 0 0 0 0 % D
% Glu: 8 54 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 54 % F
% Gly: 0 0 0 54 0 0 0 0 0 0 0 8 0 0 8 % G
% His: 0 0 0 0 0 0 0 8 0 0 0 54 0 0 0 % H
% Ile: 8 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 8 0 8 8 8 8 0 0 0 8 0 8 0 8 % K
% Leu: 16 16 0 0 8 0 8 0 0 8 0 8 0 8 16 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 8 0 8 0 47 8 8 8 54 0 24 8 8 16 0 % P
% Gln: 54 8 8 0 0 8 0 8 8 62 0 0 8 8 0 % Q
% Arg: 0 0 0 8 0 8 0 0 8 0 0 0 0 8 0 % R
% Ser: 0 0 8 8 0 8 8 8 8 0 0 0 0 47 0 % S
% Thr: 0 0 8 0 8 0 8 54 0 16 54 8 54 8 8 % T
% Val: 0 0 0 8 0 0 0 0 0 0 8 8 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 0 0 54 0 8 0 54 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _